Deslorelin

Deslorelin Structure

Name: Deslorelin; 57773-65-6; Somagard; D-Trp LHRH-PEA; Bachem 9022
CAS No.: 57773-65-6
Peptide Sequence: Pyr-His-Trp-Ser-Tyr-DTrp-Leu-Arg-Pro-NHEt
Molecular Formula: C64H83N17O12
Molecular Weight: 1282.45
Appearance: White Lyophilized powder

Deslorelin is a synthetic nonapeptide analogue of the natural gonadotrophin releasing hormone (GnRH) with potential antineoplastic activity. Deslorelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Continuous, prolonged administration of goserelin in males results in pituitary GnRH receptor desensitization and inhibition of pituitary secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)