GLP-1 (1-37)

GLP-1 (1-37) Structure

Name: Glucagon-Like Peptide 1 (1-37); GLP-1 (1-37) (Human, Bovine, Guinea Pig, Mouse, Rat); Glucagon-Related Peptide I (Ox)
CAS No.: 87805-34-3
Peptide Sequence: His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Molecular Formula: C186H275N51O59
Molecular Weight: 4169.48
Appearance: White Lyophilized powder

GLP-1 (1-37) Overview

GLP-1 receptor agonists (GLP-1RA) can mimic the physiological effects of GLP-1 and prolong the duration of action. GLP-1 and glucose-dependent insulin-stimulating polypeptide (GIP) are the two major incretins, the former of which is significantly reduced in type 2 diabetes (even those with impaired glucose tolerance) and thus becomes an important therapeutic target. Research on the physiological role of GLP-1 has shown that it can not only enhance the β-cell response, but also reduce glucagon secretion by acting on α-cells, thereby reducing hepatic glucose output, and acting on the feeding center and stomach, suppressing appetite and slowing down Gastric emptying, thereby reducing beta cell load, etc.

Product use: This product is only for research chemicals.