Glucagon

Glucagon Structure

CAS No.: 16941-32-5
Peptide Sequence: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
Molecular Formula: C153H225N43O49S
Molecular Weight: 3482.75
Appearance: White Lyophilized powder

Glucagon Overview

The main function of glucagon is to promote glycogenolysis and generate glucose to increase blood sugar; secondly, it can also increase the level of cyclic adenosine monophosphate (cAMP) through adenylate cyclase, thereby activating protein kinases and activating adipose tissue. lipase in the myocardium, promotes fat decomposition; activates the cardiac adenylate cyclase system, promotes the activity of cardiac phosphorylase, increases the accumulation of calcium in the myocardium, thereby enhancing myocardial contractility, increasing cardiac output and increasing blood pressure; also Can promote the secretion of insulin, somatostatin, thyroxine and calcitonin; promote the release of catecholamines from sympathetic nerves and chromaffin cells. Glucagon, insulin and somatostatin regulate each other to maintain blood sugar within the normal range. The secretion of glucagon is inversely proportional to the concentration of blood glucose, and the secretion of glucagon is also affected by amino acids, plasma free fatty acids, α-adrenergic receptor stimulators (norepinephrine), growth hormone-releasing inhibitory hormones.

Product use: This product is only for research chemicals.