CJC1295 with DAC

Product Information

Name: CJC1295 With DAC; CJC-1295 DAC; CJC-1295 with dac
CAS No.: N/A
Peptide Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2
Molecular Formula: C165H269N47O46
Molecular Weight: 3647.28
Appearance: White Lyophilized powder

CJC-1295 Overview

Growth hormone releasing hormone(GHRH) has been modified a number of times to produceanalogues that preserve some of the hormone’s effects while eliminating others.One of thosemodifications, CJC-1295, consists of just the first 29 amino acids of GHRH.This analogue ofGHRH, which is technically a maleimido derivative of hGRF(1-29), was created in an effort toproduce a more soluble GH secretagogue that is easier to produce in large quantities but stilpreserves the physiologic actions of GHRH.

CJC-1295 Versus CJC-1295 DAC

CJC-1295 is a modified version of the first 29 amino acids of GHRH, which means it is chemicallysimilar to other GHRH analogues, like Sermorelin. It is most similar to modified GRF (1-29), butthe two peptides are not identical. A great deal of confusion arises because of the similaritiesbetween these peptides and because CJC-1295 was originally created with an added chemicalcompound called the drug affinity complex (DAC).

DAC is added to the molecule, with the help of a lysine linker, to protect the peptide while it
circulates in the blood stream.By allowing peptides to bind to the common blood protein albumin,DAC helps to ensure that the half-life of CJC-1295 is much longer than similar molecules like GRF(1-29).

Product use: This product is only for research chemicals.